I recently joined the TNH Lab as a PhD student in Chemical Engineering in the Department of Applied Science and Technology (DISAT). I obtained my Master degree in Nanotechnologies for ICTs at Politecnico di Torino, and before starting the two-year Masters program, I graduated from the same Ateneo with a degree in Physical Engineering.
I worked at my Masters Thesis for eight months in the Department of Nanomedicine at the Houston Methodist Research Institute located in Houston (Texas, USA). My thesis research was primarily focused on the study of the radio-enhancement effects of gold nanoparticles (AuGNPs) to treat lung cancer. I collaborate to develop and assess this synergic system in different biological environments: cancer cells, fecundated chicken eggs and mice.
At the end of this experience, I spent 6 months working with a research scholarship in DISAT at the Politecnico di Torino, as a member of the Prof. Valentina Cauda’s laboratory. My work was focused on the evaluation of generation of radical species from zinc oxide nanocrystal and their internalization into cells. I’m now glad to continue this work in the TNH Lab as a PhD student and now I’m learning how to culture and perform in vitro test for cytotoxicity and internalization of ZnO nanocrystal on different adhesion or suspension cells line. I am also investigating the generation and the effects of radical species using different instruments, as cavitometer or Electron Paramagnetic Resonance (EPR) system.
In my research work, I’m particularly interested in understanding and investigating synthesis, surface functionalization, bio-imaging capabilities, and other properties of nanoparticles and how this aspects can influence the interaction of this technology with biological systems, as living cancer cells, especially when the aim of this nanotool is related to therapeutic and diagnostic application for cancer therapy.
Limongi, M. Canta, L. Racca, A. Ancona, V. Vighetto, S. Tritta, V. Cauda “Improving dispersal of therapeutic nanoparticles in the human body“, NANOMEDICINE, 2019, doi: 10.2217/nnm-2019-0070 in press